The Unit of Endocrinology and Genetics of Fertility is part of the Department of Fertility and IVF at Shaare Zedek Medical Center. The unit deals primarily with two subjects: 

Pre-Implantation Genetic Diagnosis (PGD)
Embryos created during IVF can be genetically examined for hereditary diseases before being transferred to the uterus. We sample one or two cells from the embryos achieved during IVF and, following a genetic screening, transfer only healthy embryos. The process is done in full cooperation with the Institute of Medical Genetics. This allows for the birth of healthy babies to parents with a high risk of passing on a genetic disease, to couples who have experienced multiple miscarriages, to older women who require IVF to conceive etc. This way the couple can avoid invasive examinations during the pregnancy as well as the need to consider terminating the pregnancy. 
The unit's laboratory staff excels in their ability to sample eggs and embryos in different stages of maturations and freeze sampled embryos. Our achieved pregnancies rate is over 40% - among the highest in the world. 
In addition to the use of advanced biotechnological equipment, we are attentive to the personal, mental, professional and religious needs unique to each family. We are aware that many families experience loss of sick children, prolonged infertility and various genetic diseases. We help our patients with the different aspects of the treatment and the decision-making process. 

Endocrinology of fertility
Most of our work is dedicated to evaluating women's ovarian reserve. Contrary to common perception, female fertility decreases long before menopause. On the other hand, the average parenthood age constantly increases. Many women postpone parenthood due to their professional lives, others because they haven't found the right partner yet. In this reality it's vital that a woman know how long can she successfully conceive.
Each woman is born with all the eggs she'll ever have. Therefore at any given moment she has a certain reserve. When a woman undergoes fertility treatments, it's important to ascertain this reserve to correctly evaluate her chances of conceiving now and later on, and to determine the type or treatment, which medication to use and in what dosage, in order to get the optimal amount of eggs while avoiding ovarian hyperstimulation and the accompanying complications. 
There are several markers that help us determine the ovarian reserve. The hormone AMH is one of the most reliable markers to determine the chances of conceiving (naturally or through IVF). The hormone plays a vital role in regulating the development of the follicles and the eggs in the ovary. Its level in the blood indicates the number of follicles and eggs that are at their earliest stages of development. Another marker is an ovarian ultrasound. During the examination we count the number of tiny follicles found in each ovary at the beginning of the monthly cycle (AFP - Antral Follicles Count). These markers and others allow us to evaluate each woman's "ovarian age" and, accordingly, the length of her fertility period. 
Even when IVF is done due to a fertility problem of the man, because the woman undergoes most of the treatment, it's important to give her the correct treatment and ascertain her reaction to it..
The unit also helps women about to receive chemotherapy or radiotherapy, women that received these treatments due to cancer or an autoimmune disease and single women who are interested in social egg preservation (egg freezing). The evaluation in these cases is meant to help the women in making the right decision about the best way to preserve their future fertility. 
We also diagnose and treat women with endocrinology problems that lead to infertility, such as Turner Syndrome, Fragile X mutation, Prader Willi Syndrome, obesity-related syndromes, thyroid- and adrenal-related syndromes, PCOS etc.